Self-mixing interferometry and its applications in noninvasive pulse detection

jzopen · 发表于 2013-1-15 15:29:25

目录
Abstract
Acknowledgements
List of terms, symbols and abbreviations
List of original papers
Contents
1 Introduction ...................................................................................................................15
1.1 Motivation to this work ..........................................................................................15
1.2 Laser Doppler technique in biomedical optics........................................................17
1.3 Contents of this work..............................................................................................18
2 Self-mixing interferometry ............................................................................................20
2.1 Short introduction to interferometry .......................................................................20
2.2 The self-mixing effect and its historical phases ......................................................21
2.3 Theory of self-mixing interferometry .....................................................................22
2.4 Experimental measurements based on the self-mixing effect .................................26
2.4.1 Velocity measurement......................................................................................26
2.4.2 Displacement measurement .............................................................................28
3 Cardiovascular pulsation ...............................................................................................31
3.1 Noninvasive cardiovascular pulse measurement from the wrist.............................31
3.2 Structure and radial dilation of the arterial wall......................................................33
3.2.1 Structure of the arterial wall ............................................................................33
3.2.2 Radial dilation of the arterial wall ...................................................................34
3.2.2.1 Approach using the Navier-Stokes equation .............................................35
3.2.2.2 Approach using Bernoulli’s law................................................................36
3.3 Pulse wave velocity and autonomic regulation.......................................................38
3.3.1 Pulse wave velocity .........................................................................................38
3.3.2 Autonomic regulation ......................................................................................39
4 Measurement system .....................................................................................................42
4.1 Measurement probe ................................................................................................42
4.2 PC interface card.....................................................................................................43
4.3 Data acquisition and signal processing ...................................................................43
4.4 Composition of Doppler signal from radial artery..................................................44
5 Self-mixing interferometry in cardiovascular pulse measurements...............................47
5.1 Pulse detection ........................................................................................................47
5.1.1 Normal blood pressure pulse ...........................................................................47
5.1.2 Abnormal blood pressure pulse........................................................................49
5.2 Pulse shape measurements......................................................................................50
5.3 An example of signal degradation...........................................................................52
5.4 Autonomic regulation measurement .......................................................................53
5.5 Evaluation of elasticity and pulse wave velocity ....................................................56
6 Discussion......................................................................................................................60
6.1 Measurements .........................................................................................................61
6.2 Future research........................................................................................................62
7 Summary........................................................................................................................64
References ........................................................................................................................66

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